AF-500™ Automated Fill and Seal System

Moving from concept to commercialization, the CellSeal AF-500 delivers the automation difference in a precision engineered, GMP compatible, fill-finish system.

  • Automatic sterile filling and sealing of vials (ten 2 mL or 5 mL vials per set)
  • Fills and seals up to 400 CellSeal vials per hour*
  • Transfers source material through needleless Luer fittings on the nozzle and the vials
  • Customizable vial fill volume

Handling your solution with care

  • Source material is protected from heat exposure during sealing state
  • Filling accuracy is >99% for fill volumes from 0.8 mL to 5 mL

Data collection

  • Remote software records and stores process parameters of the system during operation
  • Temperature of your source material may also be recorded
* Rate may vary with fill volume and product-specific flow limitations.

User specifications

  • Use in biosafety cabinet, isolators, or controlled benchtop environment
  • Electricity (108-125/220-245 VAC 50/60 Hz)
  • Compatible with vaporized hydrogen peroxide sterilization

System dimensions
117.5 cm wide x 50.7 cm high x 50 cm deep

Electronic control cabinet dimensions
60 cm wide x 45.1 cm high x 21 cm deep

AF-500 in-hood assembly: 95 kgs
Electrical cabinet: 30 kgs


For questions about our CellSeal vials and system of products.
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CellSeal Cryogenic Vials 10Set

DescriptionQuantity Per BoxRPNOrder Number
2 mL Needleless 10Set10 packs of 10 vialsCSV-047-10SETG47620
5 mL Needleless 10Set10 packs of 10 vialsCSV-049-10SETG47622

Connection Kit

DescriptionQuantity Per PackageRPNOrder Number
Transfer kit1 per packageTK-500 G57458

We will be closed on Tuesday 25 Dec 2018 and Tuesday 01 Jan 2019, in observation of Holidays. Please contact to discuss limited shipment schedules in your region, during this time period. Thank you!